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Fig. 1. Invasion of Rickettsia conorii is dependent on host actin polymerization. (A) In Vero cells infected with R. conorii; F-actin (green, left panel) colocalizes with invading bacteria (red) within 15 minutes of infection, as shown in the merged image (yellow, right panel). (B) Preincubation of Vero cells with cytochalasin D diminished the ability of R. conorii to invade. Bar, 2 µm.