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Fig. 7. Functional deficiency of epidermal membrane integrity in tsp-15 hypomorph C. elegans. (A,B) Pdpy-7::gfp expression patterns merged with the Nomarski images in the tsp-15(sv15) and bli-2(e768) backgrounds. In tsp-15(sv15) mutants, but not in bli-2(e768) mutants, GFP fluorescence is observed within blisters (arrows), suggesting that cellular components have leaked into the blisters in tsp-15 mutants. Small arrowheads indicate the edge of the blisters in bli-2(e768) mutants. Bars, 50 µm.