Fig. 1. Characterization of human Xin. (A) The structure of human Xin and recombinant constructs used for actin-binding and transfection assays. Xin repeats (XR) are indicated by blue boxes. The constructs are named according to the numbers of the repeats they encode. Amino acid residues for the respective constructs are indicated. (B) The sequence of the 16 human Xin repeats and their consensus sequence (lower line; in italic). Identical amino acids at each position are shaded in different colours and conserved residues are grey. (C,D) Circular dichroism spectra of native and/or denatured recombinant Xin repeats in the near (C) and far (D) UV ranges.