Fig. 3. p300 and p73 reciprocally regulate the PDGFRB promoter through the CCAAT motif. (A) The SacI/SacI promoter construct was co-transfected to NIH3T3 cells with vector alone (mock), p73, p300 or various amounts of p300 and p73, as indicated. (B) The SacI/SacI construct was co-transfected with mock vector, p73, P/CAF or various amounts of P/CAF and p73. Values represent mean luciferase activity and error bars indicate standard deviation of triplicate samples.