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Fig. 6. LRP6 co-precipitates with PTP{zeta}. (A), (B) COS-7 cells were co-transfected with LRP6-FLAG and PTP{zeta}, or with each alone. After precipitation with anti-PTP{zeta} antibody (A) or anti-FLAG antibody (B), the immunoprecipitates were probed for the presence of LRP6-FLAG (A) or PTP{zeta} (B) by immunoblotting using anti-FLAG antibody (A) or anti-PTP{zeta} antibody (B). (C) COS-7 cells were co-transfected with LRP6-FLAG, PTP{zeta} and {alpha}6-HA. After precipitation with anti-HA antibody, the immunoprecipitate was probed for the presence of LRP6-FLAG or PTP{zeta}.