Fig. 6. (A) Effect of embryo culture during the eight-cell stage in T6 plus BSA plus BV11 or BV12 anti-JAM-1 antibodies compared with control IgG2b antibody (all at 5 µg ml^–1) on timing of compaction (mean of 89 embryos per treatment). (B) Effect of embryo culture from compaction in media as above on timing of cavitation (mean of 50 embryos per treatment). Rates of cavitation significantly lower than in control medium are indicated with asterisks: *P<0.005; **P<0.0001.