Fig. 8. Taxol induces rapid dissociation of tau from MTs in a human cell line. Fluorescence images of a 356 fibroblast expressing GFP-tau. The first image was acquired immediately before application of taxol (1 µM). The time after taxol application is given in seconds. Individual MTs (arrows) and MT bundles (arrowhead) are becoming progressively dimmer, whereas the level of background cytoplasmic fluorescence increases during incubation. Bar, 10 µm.