Fig. 7. Electron microscopy of the aggresome in a HeLa cell expressing TPPP/p25. (A) Aggresome-like body (marked by arrows) located in the cavity of a crescent-shaped nucleus. (B) High-power magnification of the area boxed in A showing the heavy accumulation of microtubules and intermediate filaments in this region. Golgi cisternae (G) and mitochondria (M) are located around the body. Bar, 600 nm (A); 300 nm (B). N, nucleus.