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Fig. 2. Characterization of the MO25{alpha} WEF-binding site. (A) Structure of the WEF-binding pocket of MO25{alpha} (ribbon + surface) in which the residues interacting with the WEF motif (sticks with green carbons) of STRAD{alpha} are labelled. (B,C) HEK293 cells were transfected with the indicated constructs and analysis performed as described in the legend to Fig. 1A. Results shown are the mean±s.d. of two independent assays carried out in triplicate.