Fig. 2. Characterization of the MO25
WEF-binding site. (A) Structure of the WEF-binding pocket of MO25
(ribbon + surface) in which the residues interacting with the WEF motif (sticks with green carbons) of STRAD
are labelled. (B,C) HEK293 cells were transfected with the indicated constructs and analysis performed as described in the legend to Fig. 1A. Results shown are the mean±s.d. of two independent assays carried out in triplicate.