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Fig. 6. Inhibition of Rab7 prevents dynein recruitment to SCVs. Representative confocal micrographs showing dynein distribution (red in merged images) in GFP-Rab7-(upper panel), GFP-Rab7-T22N-(middle panel), or GFP-RILP-C33-expressing cells (lower panel) infected with S. typhimurium (WT, green in merged images) for 10 hours. Vacuolar membrane integrity was assessed by labelling LAMP-1 (blue in merged images). Scale bar: 5 µm.