Fig. 5. The centrosomal localisation of CP60 is specifically disrupted in Cp190 mutant cells. (A) The distribution of CP60 (black and white panels, red in merged images), microtubules (green), and DNA (blue) in typical wild type (WT) (left panels) and Cp190 mutant (right panels) brain cells in anaphase. CP60 is not detectable at the centrosomes of Cp190 mutant cells. (B) The centrosomal localisation of CNN (red in merged image) and
-tubulin (green in merged image) is not disrupted in Cp190 mutant cells. DNA is shown in blue in the merged image. Scale bar: 10 µm.