Fig. 7. Cartoon of the cell cycle in T. brucei trypomastigotes. (A-D) Procyclic form. (E-H) Bloodstream forms. Apart from differences in cell shape between the two forms, the segregation of the kinetoplast is more limited in the bloodstream form (G) than in the procyclic form (C). (D) In the procyclic form, the new kinetoplast and nucleus are located towards the posterior end of the cell, but the orientation of the nuclei in a post-mitotic bloodstream cell are not in the same configuration (H). The two kinetoplasts are located at the posterior end of the cell and the nuclei are both located anterior to the kinetoplast.