Fig. 1. Schematic of human CAP350. The CAP350 cDNA is predicted to encode a protein of 3117 amino acids. The locations of the conserved CAP-Gly domain and of the two putative LxxLL nuclear hormone receptor-interacting signature motifs in CAP350 are indicated. KM3 indicates the extent of two independently isolated, partial HeLa cell cDNA clones obtained from yeast two-hybrid screens for PPAR-interacting proteins (Miyata et al., 1996) and corresponds to amino acids 572-1176 of CAP350.