JCS -- Tanoue and Takeichi 118 (11): 2347 Figure IG4

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Fig. 4. Potential signaling cascades in Fat-dependent regulation of planar cell polarity (PCP). Four-jointed and Dachsous regulate (probably negatively) Fat. How Four-jointed and Dachsous regulate Fat and how Fat regulates the PCP pathway have not been currently clarified.