Fig. 3. The mRNAs for the Arp2/3 complex are localized to protrusions in fibroblasts. Images show representative poly-A RNA and ß-actin and Arp2/3-complex mRNA distributions in chicken embryo fibroblasts and human foreskin fibroblasts as detected with FISH-TSA. The fibroblasts have enriched Arp2/3-complex mRNA in their protrusions (arrows). In some cells, a proportion of the ß-actin and Arp2/3-complex mRNA can also be found at the trailing protrusion of the cells (arrowheads). Poly-A RNA appears to be distributed uniformly.