Fig. 2. HOXA3 upregulates MMP-14 and uPAR in endothelial cells. (a) Northern blot analysis of uPAR and MMP-14 expression in control and HOXA3-transfected HMEC-1. Bottom panel shows relative RNA loading visualized by ethidium bromide staining of rRNA. (b) Western blot analysis of uPAR protein in control and HOXA3-transfected EC (upper panel). Lower panel, western blot of MMP-14 in cell lysates from control or HOXA3-transfected HMEC-1.