Fig. 3. (A) Representative confocal fluorescence images of nuclear envelope permeability for 20 kDa FITC-dextran, nuclear fluorescence respectively, in response to triamcinolone acetonide (TA) and solvent at a time scale of 5 minutes after injection into glucocorticoid receptors-expressing X. laevis oocytes. (B) Change of nuclear envelope permeability for 20 kDa FITC-dextran, nuclear fluorescence respectively, in response to triamcinolone acetonide (TA) and solvent at a time scale of 5 and 60 minutes after injection of TA into glucocorticoid receptor-expressing X. laevis oocytes. Asterisk (*) indicates a statistically significant difference (unpaired t-test, P<0.0009) between the mean data of solvent and TA experiments.