Fig. 5. CI-976 does not inhibit initial uptake of Tf. TRITC-Tf was pre-bound to the surface of Clone 9 cells at 4°C. Following 15 minutes treatment with either (A) DMSO as a solvent control or (B) 20 µM CI-976 at 4°C, the cells were shifted to 37°C for 5 minutes to allow Tf uptake.