Fig. 3. Comparison of the distributions of each of the SCAMPs (SC1-SC4) to markers that localize to perinuclear and peripheral compartments in differing patterns. (A-D) Transferrin receptor (TfR), (E-H) EEA-1 (EEA1), (I-L) TGN-38 (TGN38) and (M-P) syntaxin 6 (syn6). SC1 and SC3 staining is also compared to mannose-6-phosphate receptor (M6PR) (Q,R) and to CD63 staining (CD63) (S,T). All images are digitally deconvolved sections, and the insets highlight differing degrees of overlap in the perinuclear region. Bar, 10 µm.