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Fig. 3. Effects of various concentrations of cromakalim on the [Ca2+]i oscillation frequency. Changes in the frequency are plotted for individual cell cluster preparations. The graph in A shows the effects of 1 (filled circles) or 3 µM cromakalim (open circles) applied in normal extracellular medium. In B, 10 µM cromakalim (filled triangles) was used in the presence of 1 µM nifedipine.