Fig. 4. Effects of cromakalim on the [Ca²⁺]_i oscillation amplitude. The amplitude of [Ca²⁺]_i oscillation is expressed relative to that before application of cromakalim. The experiments for 10 µM cromakalim (Crm) were carried out in the presence of nifedipine (1 µM). The number of experiments is shown in brackets. The effect of 10 µM cromakalim was significantly inhibited by a prior application of 1 µM glybenclamide (Glib) (P<0.05, indicated by an asterisk).