Fig. 4. Tau and -synuclein each co-immunoprecipitate with kinesin-1, whereas only -synuclein co-immunoprecipitates with dynein. Rat brain homogenate was immunoprecipitated using antibodies recognising tau (left panels) or -synuclein (right panels). Immunoprecipitates were analysed on western blots with antibodies to kinesin-1 (upper panels) or dynein (lower panels). The tau antibody co-immunoprecipitated kinesin-1 but not dynein. The antibody to -synuclein co-immunoprecipitated both kinesin-1 and dynein. Molecular mass markers are shown on the left (kDa).