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Fig. 5. Effects of various kinase inhibitors on RA-induced synaptic facilitation. The continuous traces A-F show the effect of RA on the SSC frequency in the presence of a PKC inhibitor, H-9 (100 µM), BIS (bisindolmaleimide, 10 µM), a board-spectrum tyrosine kinase inhibitor, genistein (100 µM), an inactive analog of genistein, daidzein (100 µM), a Src tyrosine kinase inhibitor, PP2 (10 µM) or a MAP kinase inhibitor, PD98059 (10 µM). Downward deflections are SSCs (Vh=–70 mV). Scale bars: 1 nA, 20 seconds.