JCS -- Churchward et al. 118 (20): 4833 Figure IG11

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Fig. 11. Addition of negative curvature lipids to cholesterol-depleted CVs. (A) Ca²⁺-activity curves of untreated CVs (n=3), CVs treated with 2 mM mßcd (n=3), or CVs treated with 2 mM mßcd and then with 10 µM ${alpha}$ -tocopherol (n=3) or 10 µM DOPE (n=3). Vertical dashed lines indicate the EC50 of each curve. (B) Fusion kinetics of CVs treated as in A, in response to 111±14 µM [Ca²⁺]_free (n=3).