Fig. 5. Epistasis analysis of the set1
and clb5
mutations. Frequencies of nuclei displaying a single centromere FISH signal (% cen cluster), with two to eight perinuclear telomere FISH signals (% veg tel cluster) or with a single telomere FISH signal cluster (% bouquet) in clb5
and set1
clb5
strains, at the indicated time points after transfer into sporulation medium. Top: clb5
and set1
clb5
FACS profiles aligned to the corresponding time points.