Fig. 2. Cajal bodies and PML bodies can associate with the same U2 gene locus. HeLa cells were subjected to antibody staining to mark the location of CBs (red) and PML bodies (blue), followed by DNA FISH using an U2 gene probe (green). The arrow marks an association between CBs, PML bodies and an U2 gene (inset) in four different cells. Scale bar, 2 µm.