Fig. 7. Comparison of monomeric and dimeric N-cadherin-Fc in supporting adhesion of DX3 melanoma cells. Cadherin preparations, shown to be monodisperse, were titrated onto an assay plate coated with goat anti-human Fc. DX3 cells were applied and adhesion was assessed as described. Dimeric N-cadherin-Fc containing the mutations W2G and D134A provided a negative control.