(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. BBS6 is localized within the pericentriolar material (PCM) tube and shows a dynamic distribution during the cell cycle. (A) High-resolution digital microscopy optical sections of NIH 3T3 cells co-stained with antibodies against BBS6 (green) and {gamma}- and acetylated-tubulin (red). (B) Optical sections of BBS6 (green) and PCM tube (red) signals in the same focal plane from interphase or mitotic HeLa cells. The PCM tube was detected using an antibody, M4491, that recognizes multiple PCM components. Closeups of the PCM tube (insets), BBS6 and merged signals are also shown.