Fig. 8. Organization of the exocyst complex. Interactions are depicted for members of the exocyst complex with each other and with an unknown receptor on the plasma membrane (left), based on a slight modification of the model derived from studies in yeast (Guo et al., 1999) and in accordance with the data from Figs 6, 7. In sec5 mutants, Sec8 is no longer associated with the membrane and other subunits might also become cytosolic (center). In sec6 mutants, however, both Sec5 and Sec8 can remain membrane associated (right).