JCS -- Formigli et al. 118 (6): 1161 Figure IG7

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 7. Effects of S1P and of chemical treatments on membrane current and conductance. Voltage-clamp step pulses between –80 and 0 mV in 10 mV steps from a holding potential of –60 mV were applied to the cells for 100 milliseconds. Representative current traces in control (A) and after S1P (B), GdCl₃ (C), S1P + GdCl₃ (D), DHCB (E) and S1P + DHCB (F) treatments. G, normalized I_m versus Vm plots in Control condition ( ${blacksquare}$ ) and after S1P ( ${bullet}$ ) or GdCl₃ ( ${triangleup}$ ) or S1P + GdCl₃ ( ${blacktriangleup}$ ) or DHCB( ${diamond}$ ) or S1P + DHCB( ${diamondsuit}$ ) treatment. The best linear regression lines are superimposed on control (continuous line) and the other experimental conditions (dashed lines). The calculated C_m, G_m and G_m/C_m values for all experimental conditions are reported in Table 1. Data are the mean±s.e.m.