Fig. 1. FGFR2 activation reduces osteoblast attachment on bone matrix proteins. FGFR2 mutant and control (wild-type) cells were cultured on fibronectin-coated dishes (A) or type I collagen-coated dishes (B) for the indicated times, or on fibronectin at the indicated concentration for 1 hour (C), and the number of attached cells was recorded. * Indicates a significant difference compared to number in control cells (P<0.05). The data are the mean±s.e.m. (n=3-6) and are representative of three separate experiments.