JCS -- Griffin et al. 118 (7): 1405 Figure IG6

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 6. Phosphoprotein comparisons of normal and ${gamma}$ SG-deficient TA muscle. (A) Immunoblots of tissue lysates show significant activation of ERK-1 and downregulation of adducin- ${gamma}$ phosphorylation with no changes in cofilin in ${gamma}$ SG^–/– tissue compared with control tissue. (B) Blots of stretched and unstretched ${gamma}$ SG^–/– tissue show hyperactivation of p38 MAPK, ERK1/2, MAPKAP2 and Smad1 in stretched tissue.