Fig. 1. Cell-cycle distribution of MEFs. Cells were treated for 12 or 24 hours with adriamycin (345 nM) and fixed. The DNA content of propidium iodide-stained cells was determined by FACS. (A) Flow cytometry profiles of MEFs treated with adriamycin. (B) Percentage of MEFs in different phases of the cell cycle. Standard errors are shown.