JCS -- Callow et al. 118 (9): 1861 Figure IG7

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Fig. 7. (A) GEF-H1 in a non-phosphorylated state retains basal constitutive Rho activity. (B) PAK4 can regulate GEF-H1 by phosphorylation leading to simultaneous Rac activation and inhibition of constitutive Rho signaling.