JCS -- Xia et al. 119 (10): 2138 Figure IG1

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Fig. 1. Knocked-in ${alpha}$ 3 connexin suppresses the severe cataract caused by the ${alpha}$ 8-G22R mutation. Comparison of three compound mutant lenses of mice aged 3 weeks. (A) The ${alpha}$ 3(-/-) ${alpha}$ 8(KI ${alpha}$ 3/-) lens is transparent. (B) The ${alpha}$ 3(-/-) ${alpha}$ 8(G22R/-) lens has severe cataract with posterior rupture. (C) The ${alpha}$ 3(-/-) ${alpha}$ 8(G22R/KI ${alpha}$ 3) lens is intact with only a very mild nuclear cataract.