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Figure 7


Fig. 7. MORN1 in apicomplexan cell division. MORN1 is shown in green, tubulin and centrosome in red, IMC in dark blue and the nucleus in light blue. (A) The centrocone persists through interphase. (B) The centrosome duplicates and sets up the mitotic spindle, splitting the centrocone into two. (C) Mitosis occurs and apical and posterior MORN1 rings form for each daughter. (D) During budding, subpelicular microtubules push the MORN1 rings down while the spindle pushes the centrocones up. Microtubule driven movements are indicated by red arrows, constriction is shown in green (C,D). (E) Schematic representation of the centrocone: C, centrosome; CC, centrocone; MT, microtubules; NE, nuclear envelope; K, kinetochores. (F) A model for the structure and function of the posterior ring in daughter buds.