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Figure 2


Fig. 2. Pharmacological inhibition of proteasomal degradation favors sRB formation. N[µ{Delta}CH1] cells were cultured for 24 hours with or without 1 mM sodium butyrate (NaBut). Aliquots of cells treated with NaBut were exposed to MG132 for the last 2 hours in culture. The histogram depicts the percentage of cells containing µ{Delta}CH1 sRB structures and represents the average of two independent experiments.