Fig. 6. p75 tethers JPO2 to chromosomes. 293T-si1340/1428 cells depleted for endogenous p75 or control 293T-siScram cells were transfected with the EGFP-JPO2 expression construct. At 48 hours post-transfection, fixed cells were immunostained for p75 (red). EGFP-JPO2 was detected by epifluorescence (green) and DNA by staining with DRAQ5 (blue). Bars, 10 µm.