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Figure 4


Fig. 4. Effects of lysenin on CV fusion. (a) Ca2+-activity curves following treatments with lysenin, before (n=8) and after CV exposure to SMase (10 U/ml) (n=4). Vertical dotted lines indicate the EC50 of each curve. (b) Kinetics of CV fusion triggered with 86.9±5.8 µM [Ca2+]free after treatment with 0 and 0.6 nM lysenin (n=8).