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Figure 2


Fig. 2. P-RPA and {gamma}H2AX accumulate at camptothecin-induced DNA repair foci in Vero cells. Vero cells were treated with 1 µM camptothecin (CPT) for 5 hours and prepared for IF analysis as described in the legend to Fig. 1. Cells were double labeled to detect the localization of {gamma}H2AX (green) and P-RPA (red). The merged image shows a significant colocalization of the two signals (yellow). 100x magnification with 2x zoom.