JCS -- Desban et al. 119 (15): 3206 Figure IG6

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Fig. 6. Crest cell response to LN-1 is mimicked by antibodies against ${alpha}$ 1ß1 integrin adsorbed to the substrate. (A-C) Adhesion, spreading and migration on LN-1 and antibodies against ${alpha}$ 1ß1 or ${alpha}$ 6ß1 integrin. (D,E) Morphology and migration of crest cells on antibodies against ${alpha}$ 1ß1 and ${alpha}$ 6ß1 at 50 µg/ml. Bar, 100 µm; nt, neural tube. (F) Cell survival on LN-1 at 25 µg/ml (squares) and on antibodies against ${alpha}$ 1ß1 (triangles) and ${alpha}$ 6ß1 (circles) at 1, 10 and 50 µg/ml. (G,H) Morphologies of crest cells cultured for up to 48 hours on antibodies against ${alpha}$ 1ß1 or ${alpha}$ 6ß1 at 50 µg/ml. Note the presence of neurons on the antibodies against ${alpha}$ 1ß1.