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Figure 10


Fig. 10. Increasing securin levels restores coordination of mitotic events in separase S1126A cells. (A) Time-lapse sequence of a separase S:A cell expressing dsRed showing premature loss of cohesion. (B) Time-lapse sequences of separase S:A cells expressing securin-dsRed proteins, showing rescue and cut phenotypes. (C) Quantitation of phenotypes following expression of securin-dsRed fusions in separase S:A cells.