JCS -- Holland and Taylor 119 (16): 3325 Figure IG9

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Fig. 9. Securin degradation is not required for the premature loss of cohesion in separase S:A cells. Time-lapse sequences and pixel-intensity measurements showing securin-dsRed fluorescence in (A) control or (B) Separase-S:A-expressing cells. Whereas securin-dsRed is degraded prior to chromatid disjunction in the control cell, it is not degraded until mitotic exit in the separase S:A cell.