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Figure 4


Fig. 4. MT1-MMP and MMP-9 are upregulated in the epilysin-expressing pools. (A,B) Polypeptides in the conditioned media from the A549 cell pools were immunodetected with antibodies against matrilysin (A) and MT1-MMP (B). (C) The content of gelatinases in the conditioned media from the A549 cell pools was analyzed by gelatin zymography. Bands corresponding to gelatinase B (MMP-9) and gelatinase A (MMP-2) are indicated. Two additional unidentified gelatinolytic bands in the epilysin-expressing pool have been indicated with arrows.