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Figure 3


Fig. 3. Microtubule-organizing centers (MTOCs) in (A) animal cells, (B) budding yeast and (C) Dictyostelium. (A) The animal centrosome consists of a pair of centrioles surrounded by pericentriolar material (PCM). MTs are nucleated from {gamma}-tubulin ring structures embedded in the PCM. (B) The yeast spindle-pole body (SPB) is a disk-like trilaminar plug that spans both nuclear membranes and organizes astral and spindle MTs on the cytoplasmic and nuclear sides of the nuclear envelope, respectively. (C) The slime mold (Dictyostelium discoideum) interphase centrosome consists of a three-layered core surrounded by a fibrous corona, from which MTs emanate.