Fig. 7. Two possibilities exist for the orientation of
-tubulin (and consequently the
TuRC) with respect to the long axis of the MT to which it is bound. (A) Adjacent
-tubulin subunits make shoulder-to-shoulder contacts in the template model, as indicated by the red oval that marks the position of the GTP-binding pocket on
-tubulin. (B)
-tubulin subunits make head-to-tail contacts in the protofilament model.