Fig. 1. Conventional thin-section electron microscopy of macrophages lipid laden by treatment with AcLDL for 24 hours. (A) The cells contain accumulations of lipid droplets (LD) in the cytoplasm. (B,C) Examples of close association between lipid droplets (LD) and ER membranes. At the sites of association with the lipid droplet, the ER lumen becomes narrowed and ribosomes are absent. G, Golgi apparatus; M, mitochondrion; N, nucleus. Bars, 1 µm (A); 0.2 µm (B,C).