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Figure 4


Fig. 4. cPAR3 overexpression affects positioning of dividing cells within the NE. (A) Normal NEP cells, expressing a membrane-tethered GFP, move their nucleus apically and always divide near the luminal surface (red and white arrowheads). (B) Illustrative example (n=12 cells) of a GFP-gpi NEP cell overexpressing cPAR3 dividing away from the apical surface (red arrow). Bar in (A), 10 µm; (B), 20 µm.