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Figure 1


Fig. 1. Gliotactin is found at TCJs in numerous larval tissues. (A,B) Epidermal cells stained with Gliotactin at the TCJ. Gliotactin (green) is concentrated at the TCJ (arrows) compared with Dlg (red) in A or Coracle (red) in B, which label the entire SJ domain. (C,D) Tracheal cells labeled with Gliotactin at the TCJ between tracheal cells. Gliotactin (green) and Coracle (red) co-staining shows the concentration of Gliotactin at the TCJ (arrows). (E) Salivary gland cells labeled with Gliotactin (green) and Neuroglian (red). Gliotactin at the TCJ has a punctate pattern (arrow). (F) Peripodial cells from the wing imaginal disc labeled with Gliotactin (green) and Dlg (red) showing the ribbon like structure of the TCJ (arrows) which extend over several microns. (G,H) Columnar epithelial cells from wing imaginal discs labeled with Gliotactin (green) and Dlg (red) in G and the Na+/K+ ATPase {alpha} subunit (red) in H. Despite their small size, the TCJ is distinguishable from the rest of the septate junction domain (arrows). Bars, 15 µm (A,B,D-H); 20 µm (C).