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Figure 3


Fig. 3. Mapping of the versican-binding domain in TSP1. (A) [125I]-TSP1 binding to immobilized VG1 was determined in the presence of divalent cations and the indicated concentrations of full length TSP1 (bullet), NoC1 ({circ}), CP123 ({triangleup}), P3E123 ({diamond}), or E3CaG ({square}). (B) A structural model of TSP1. (C) [125I]-TSP1 binding to immobilized VG1 was determined in the presence of divalent cations and the indicated concentrations of NoC1 (bullet), NoC2 ({circ}), E3CaG ({blacksquare}), or N ({diamondsuit}).